Video: ❶ How Is The Aging Process In Cells
Aging has always been a topic of interest to humanity. Scientists at all times have tried to find out why people get old, get sick and die and how you can avoid aging of the body. The mechanism of cell aging in living organisms has been studied by a group of British and German scientists. Location: Location:
According to the research of a group of scientists, it was found that cellular aging is the loss of the ability of cells to divide and repair body tissues. The aging process in cells is caused by self-accelerating damage to the genome, while violations in DNA lead to the release of substances that activate new violations in the DNA code.
To identify the aging process of cells, scientists from the University of Newcastle (Britain) and the University of Ulm (Germany) used the latest advances in laboratory research and mathematical models of cells in living organisms. Thanks to such models, they were able to better understand the mechanism of aging.
It was found that aging is directly related to a violation of the cell's ability to divide, due to which living tissues cease to regenerate and perform their functions worse and worse. In addition, cellular aging contributes to the chaotic multiplication of cells, which leads to the emergence of cancer.
Biologists have described the molecular mechanism of cell aging in this way: there is a dynamic feedback loop triggered by a reaction to DNA damage, which after a few days brings the cell to a state of deep cellular aging.
The spiral of aging triggered by DNA damage leads to a breakdown in the functions of cellular mitochondria, which process oxygen and nutrients in cells into molecules of adenosine triphosphate, which are the source of energy for most biochemical processes in the body.
Damaged mitochondria release a huge amount of chemically active particles - free radicals, which also damage DNA. Damaged DNA again provokes the release of free radicals. The process grows, and the cell soon loses its ability to divide.
Scientists believe that the results of the study will help create drugs that affect the aging process in cells, and in the future will save people from many diseases associated with aging.